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KMID : 1123920100240020206
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Korean Journal of Oriental Physiology and Pathology
2010 Volume.24 No. 2 p.206 ~ p.219
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( Analysis of Studies on Sagunja-tang(Sijunzi-tang) to Establish the Fundament for Evidence Based Medicine )
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Kim Jung-Hoon
Lee Jun-Kyoung
Shin Hyeun-Kyoo
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Abstract
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To establish the fundament for EBM of Traditional Korean Medicine, the papers on Sagunja-tang(Sijunzi-tang) frequently used in medical institutions of Traditional Korean Medicine were analyzed through researching domestic and international papers. The papers were classified by the registration of domestic or international journals, the year of publishment, experimental fields and the kinds of studies on biological activities. Of total 228 papers on Sagunja-tang(Sijunzi-tang), 121 volumes were selected according to creteria. 47 volumes were published in domestic journals, 71 in Chinese journal, 2 in Japanese journal, and 1 in Taiwan journal. The papers on instrumental analyses were preceeded by HPLC, MS, GC with standard compounds of herbal medicine in Sagunja-tang(Sijunzi-tang). The papers on biological activities of Sagunja-tang(Sijunzi-tang) showed improvement of gastrointestinal activity and blood circulation, immunoactivity, anti-cancer, anti-oxidant, anti-fatigue, anti-stress, pharmacokinetics, hepatic protection, radioprotection, muscular activity, hematopoiesis and nontoxical effect. Further studies including gastrointestinal disorder, immune related disease, cancer, oxidative injury and pharmacokinetic study need to be preceeded to establish the fundament for EBM of Sagunja-tang(Sijunzi-tang).
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KEYWORD
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Sagunja-tang(Sijunzi-tang), Evidence Based Medicine(EBM), instrumental analysis, biological activity
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